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Body mass index

ARHGAP15 · rs13002158

Where this position leads

Conditions: Waist-to-Hip Ratio (Body Fat Distribution), Obesity and Body Weight

rs13002158 Condition: Waist-to-Hip Ratio (Body Fat Distribution) Waist-to-Hip Ratio (Body Fat Distri… Condition Condition: Obesity and Body Weight Obesity and Body Weight Condition rs13002158 rs13002158 ARHGAP15

What the study found

Who was studied 434,794 European ancestry female individuals.

The effect Each copy of the A allele shifted the measure 0.0154 lower (95% confidence interval 0.011-0.02); p = 1 × 10−12.

How common The A allele had a frequency of about 81% in the people studied.

Where it sits Chromosome 2, band 2q22.2 — in an intron of ARHGAP15.

What each result means

A/A Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
G/G No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs13002158

What is rs13002158?

rs13002158 is a single position in the genome, in or near the ARHGAP15 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13002158 linked to?

On MyGeneLog this position is linked to Waist-to-Hip Ratio (Body Fat Distribution), Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs13002158 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13002158 come from?

GWAS Catalog, Hum Mol Genet 2018, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body mass index (rs13002158). MyGeneLog™. https://www.mygenelog.com/variants/rs13002158

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