1 422226223221Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others21Total42Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
The effect
Each copy of the C allele shifted the measure 0.15 lower (95% confidence interval 0.13-0.17); p = 2 × 10−27.
How common The C allele had a frequency of about 11% in the people studied.
Where it sits Chromosome 2, band 2q12.1 — in an intron of IL1RL1.
What each result means
A/ANo copy of the version the research linked to Serum protein levels (sST2). This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Serum protein levels (sST2). That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Serum protein levels (sST2). That is the strongest link of the three results. A link in a study is not a diagnosis.
The Journal of clinical investigation · 2013 · PMID 23999434
Questions about rs12999542
What is rs12999542?
rs12999542 is a single position in the genome, in or near the IL1RL1 gene. Published research associates it with serum protein levels (sst2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12999542 linked to?
On MyGeneLog this position is linked to Serum sST2 Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs12999542 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12999542 come from?
GWAS Catalog, J Clin Invest 2013, PMID:23999434. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 422226223221Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others21Total42Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Serum protein levels (sST2) (rs12999542). MyGeneLog™. https://www.mygenelog.com/variants/rs12999542