0 3022282239Reads by AI crawlersClaude2ChatGPT2Google · Gemini2Perplexity0Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others9Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1795 African American cases, 99 African ancestry cases, 4,150 African American controls, 624 African ancestry controls; replicated in 1093 African American cases, 2939 African American controls.
The effect
Each copy of the G allele carried 1.34 times the odds of Breast cancer (estrogen-receptor positive) (95% confidence interval 1.21-1.48); p = 2 × 10−8.
How common The G allele had a frequency of about 86% in the people studied.
Where it sits Chromosome 2, band 2q35 — in an intron of TESHL.
What each result means
A/ANo copy of the version the research linked to Breast cancer (estrogen-receptor positive). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Breast cancer (estrogen-receptor positive). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Breast cancer (estrogen-receptor positive). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs12998806 is a single position in the genome, in or near the near TNP1 gene. Published research associates it with breast cancer (estrogen-receptor positive). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12998806 linked to?
On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs12998806 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12998806 come from?
GWAS Catalog, Hum Mol Genet 2016, PMID:28171663. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 3022282239Reads by AI crawlersClaude2ChatGPT2Google · Gemini2Perplexity0Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others9Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Breast cancer (estrogen-receptor positive) (rs12998806). MyGeneLog™. https://www.mygenelog.com/variants/rs12998806