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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 85,824 European ancestry individuals, 3,509 African American or Afro-Caribbean individuals, 3,337 East Asian ancestry individuals, 3,098 Hispanic or Latin American individuals.
The effect
Each copy of the T allele shifted the measure 0.071 higher (95% confidence interval 0.055-0.087); p = 1 × 10−17.
How common The T allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 19, band 19q13.33 — inside KLK2.
What each result means
C/CNo copy of the version the research linked to Prostate-specific antigen levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Prostate-specific antigen levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Prostate-specific antigen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature medicine · 2023 · PMID 37264206 · open access
Questions about rs12983994
What is rs12983994?
rs12983994 is a single position in the genome, in or near the KLK2 gene. Published research associates it with prostate-specific antigen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12983994 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12983994 come from?
GWAS Catalog, Nature medicine 2023, PMID:37264206. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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