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Who was studied 11,024 psoriasis cases, 60,801 coronary artery disease cases, 139,840 controls.
The effect
The reported allele is G; the catalogue records no effect size
; p = 3 × 10−11.
How common The G allele had a frequency of about 75% in the people studied.
Where it sits Chromosome 19, band 19p13.2 — in an intron of C19orf38.
What each result means
A/ANo copy of the version the research linked to Psoriasis or coronary artery disease. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Psoriasis or coronary artery disease. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Psoriasis or coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2022 · PMID 36323703 · open access
Questions about rs12979495
What is rs12979495?
rs12979495 is a single position in the genome, in or near the C19orf38 gene. Published research associates it with psoriasis or coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12979495 linked to?
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs12979495 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12979495 come from?
GWAS Catalog, Nature communications 2022, PMID:36323703. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Psoriasis or coronary artery disease (rs12979495). MyGeneLog™. https://www.mygenelog.com/variants/rs12979495