Standard

Body shape phenotype PC2

LILRB5 · rs12976868

What the study found

Who was studied 460,198 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.017 lower (95% confidence interval 0.012-0.022); p = 2 × 10−10.

How common The A allele had a frequency of about 78% in the people studied.

Where it sits Chromosome 19, band 19q13.42 — a synonymous change in LILRB5.

What each result means

A/A Two copies of the version the research linked to Body shape phenotype PC2. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Body shape phenotype PC2. That is a smaller link than two copies.
G/G No copy of the version the research linked to Body shape phenotype PC2. This is the starting point the study compared everyone against.
Source

Questions about rs12976868

What is rs12976868?

rs12976868 is a single position in the genome, in or near the LILRB5 gene. Published research associates it with body shape phenotype pc2. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12976868 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12976868 come from?

GWAS Catalog, Science advances 2024, PMID:38640244. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body shape phenotype PC2 (rs12976868). MyGeneLog™. https://www.mygenelog.com/variants/rs12976868

← See all variants