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Who was studied 3,037,499 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.00746 higher (95% confidence interval 0.0052-0.0097); p = 4 × 10−11.
How common The A allele had a frequency of about 68% in the people studied.
Where it sits Chromosome 19, band 19p13.13 — in an intron of ZNF490.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Educational attainment compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Educational attainment.
G/GPublished research associates this genotype with typical/baseline likelihood of Educational attainment — no copies of the reported risk allele.
Nature genetics · 2022 · PMID 35361970 · open access
Questions about rs12972944
What is rs12972944?
rs12972944 is a single position in the genome, in or near the ZNF490 gene. Published research associates it with educational attainment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12972944 linked to?
On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.
Does having rs12972944 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12972944 come from?
GWAS Catalog, Nature genetics 2022, PMID:35361970. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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