Body mass index x sex x age interaction (4df test)
MC4R · rs12955983
0 20622316Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others6Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied up to 51,625 European ancestry men aged <50, up to 60,654 European ancestry women aged <50, up to 90,988 European ancestry men aged >50, up to 106,622 European ancestry women aged >50.
The effect
The reported allele is G; the catalogue records no effect size
; p = 9 × 10−60.
How common The G allele had a frequency of about 28% in the people studied.
Where it sits Chromosome 18, band 18q21.32 — between genes, 7.3 kb from LOC342784.
What each result means
A/ANo copy of the version the research linked to Body mass index x sex x age interaction (4df test). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Body mass index x sex x age interaction (4df test). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Body mass index x sex x age interaction (4df test). That is the strongest link of the three results. A link in a study is not a diagnosis.
PLoS genetics · 2015 · PMID 26426971 · open access
Questions about rs12955983
What is rs12955983?
rs12955983 is a single position in the genome, in or near the MC4R gene. Published research associates it with body mass index x sex x age interaction (4df test). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12955983 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs12955983 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12955983 come from?
GWAS Catalog, PLoS Genet 2015, PMID:26426971. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 20622316Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others6Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Body mass index x sex x age interaction (4df test) (rs12955983). MyGeneLog™. https://www.mygenelog.com/variants/rs12955983