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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 13,409 European ancestry male cases, 98,267 European ancestry male controls; replicated in 4,426 European ancestry male cases, 32,800 European ancestry male controls.
The effect
The reported allele is G; the catalogue records no effect size
; p = 5 × 10−109.
How common The G allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 17, band 17p13.1 — in the 3′ untranslated region of CD68.
What each result means
A/ANo copy of the version the research linked to Low testosterone levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Low testosterone levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Low testosterone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
European urology open science · 2021 · PMID 34337532 · open access
Questions about rs12944954
What is rs12944954?
rs12944954 is a single position in the genome, in or near the CD68 gene. Published research associates it with low testosterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12944954 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12944954 come from?
GWAS Catalog, European urology open science 2021, PMID:34337532. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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