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Phenylpyruvate levels

near RPL12P36 · rs12932254

What the study found

Who was studied 6,136 Finnish ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.35 higher; p = 3 × 10−20.

Where it sits Chromosome 16, band 16q21 — between genes, 18.2 kb from RPL12P36.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Phenylpyruvate levels — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Phenylpyruvate levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Phenylpyruvate levels compared to the general population.
Source

Questions about rs12932254

What is rs12932254?

rs12932254 is a single position in the genome, in or near the near RPL12P36 gene. Published research associates it with phenylpyruvate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12932254 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12932254 come from?

GWAS Catalog, Nature communications 2022, PMID:35347128. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Phenylpyruvate levels (rs12932254). MyGeneLog™. https://www.mygenelog.com/variants/rs12932254

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