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Who was studied 283,749 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.128 higher (95% confidence interval 0.093-0.162); p = 6 × 10−13.
Where it sits Chromosome 16, band 16p13.3 — in an intron of LMF1.
What each result means
A/ATwo copies of the version the research linked to Height (standard GWA). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Height (standard GWA). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Height (standard GWA). This is the starting point the study compared everyone against.
Nature human behaviour · 2023 · PMID 37106081 · open access
Questions about rs12927578
What is rs12927578?
rs12927578 is a single position in the genome, in or near the LMF1 gene. Published research associates it with height (standard gwa). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12927578 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs12927578 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12927578 come from?
GWAS Catalog, Nature human behaviour 2023, PMID:37106081. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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