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Triglyceride to HDL cholesterol ratio

LMF1 · rs12924608

What the study found

Who was studied 402,398 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0223 higher (95% confidence interval 0.017-0.027); p = 5 × 10−12.

How common The T allele had a frequency of about 61% in the people studied.

Where it sits Chromosome 16, band 16p13.3 — in a non-coding transcript of LMF1.

What each result means

C/C No copy of the version the research linked to Triglyceride to HDL cholesterol ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Triglyceride to HDL cholesterol ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Triglyceride to HDL cholesterol ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12924608

What is rs12924608?

rs12924608 is a single position in the genome, in or near the LMF1 gene. Published research associates it with triglyceride to hdl cholesterol ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12924608 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12924608 come from?

GWAS Catalog, Nature genetics 2024, PMID:38200128. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglyceride to HDL cholesterol ratio (rs12924608). MyGeneLog™. https://www.mygenelog.com/variants/rs12924608

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