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white blood cell count (WBC, mean, inv-norm transformed)

near FGR · rs1292074

What the study found

Who was studied 108,896 African American or Afro-Caribbean individuals, 49,978 Hispanic or Latin American individuals, 5,839 East Asian ancestry individuals, 381,099 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0449 lower (95% confidence interval 0.035-0.055); p = 5 × 10−19.

How common The C allele had a frequency of about 84% in the people studied.

Where it sits Chromosome 1, band 1p35.3 — between genes, 12.3 kb from FGR.

What each result means

C/C Two copies of the version the research linked to white blood cell count (WBC, mean, inv-norm transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to white blood cell count (WBC, mean, inv-norm transformed). That is a smaller link than two copies.
T/T No copy of the version the research linked to white blood cell count (WBC, mean, inv-norm transformed). This is the starting point the study compared everyone against.
Source

Questions about rs1292074

What is rs1292074?

rs1292074 is a single position in the genome, in or near the near FGR gene. Published research associates it with white blood cell count (wbc, mean, inv-norm transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1292074 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1292074 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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white blood cell count (WBC, mean, inv-norm transformed) (rs1292074). MyGeneLog™. https://www.mygenelog.com/variants/rs1292074

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