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Asthma

AKAP13 · rs12916001

Where this position leads

Condition: Asthma

rs12916001 Condition: Asthma Asthma Condition rs12916001 rs12916001 AKAP13

What the study found

Who was studied 71,481 European ancestry cases, 685,602 European ancestry controls.

The effect Each copy of the G allele carried 1.03 times the odds of Asthma (95% confidence interval 1.021-1.048); p = 4 × 10−8.

How common The G allele had a frequency of about 72% in the people studied.

Where it sits Chromosome 15, band 15q25.3 — in an intron of AKAP13.

What each result means

A/A No copy of the version the research linked to Asthma. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Asthma. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12916001

What is rs12916001?

rs12916001 is a single position in the genome, in or near the AKAP13 gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12916001 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs12916001 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12916001 come from?

GWAS Catalog, Nature communications 2025, PMID:41213931. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Asthma (rs12916001). MyGeneLog™. https://www.mygenelog.com/variants/rs12916001

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