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Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level)

ARID3B · rs12909047

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) compared to the general population. (GWAS Catalog, Hum Mol Genet 2016, PMID:27702941)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level). (GWAS Catalog, Hum Mol Genet 2016, PMID:27702941)
G/G Published research associates this genotype with typical/baseline likelihood of Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) — no copies of the reported risk allele. (GWAS Catalog, Hum Mol Genet 2016, PMID:27702941)

Source: GWAS Catalog, Hum Mol Genet 2016, PMID:27702941

Questions about rs12909047

What is rs12909047?

rs12909047 is a single position in the genome, in or near the ARID3B gene. Published research associates it with caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12909047 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12909047 come from?

GWAS Catalog, Hum Mol Genet 2016, PMID:27702941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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