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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 11,272 European, Hispanic or African American individuals; replicated in 1,734 Hispanic ancestry children, 6,762 European or African American individuals.
The effect
Each copy of the C allele shifted the measure 0.241 higher (95% confidence interval 0.21-0.28); p = 1 × 10−40.
How common The C allele had a frequency of about 17% in the people studied.
Where it sits Chromosome 15, band 15q21.3 — inside ALDH1A2.
What each result means
C/CTwo copies of the version the research linked to Metabolite levels (1-palmitoylglycerophosphoethanolamine; 1-palmitoyl-GPE (16:0); C16:0 LPE; C16_0_LPE). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Metabolite levels (1-palmitoylglycerophosphoethanolamine; 1-palmitoyl-GPE (16:0); C16:0 LPE; C16_0_LPE). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Metabolite levels (1-palmitoylglycerophosphoethanolamine; 1-palmitoyl-GPE (16:0); C16:0 LPE; C16_0_LPE). This is the starting point the study compared everyone against.
Nature communications · 2023 · PMID 37253714 · open access
Questions about rs12905732
What is rs12905732?
rs12905732 is a single position in the genome, in or near the ALDH1A2 gene. Published research associates it with metabolite levels (1-palmitoylglycerophosphoethanolamine; 1-palmitoyl-gpe (16:0); c16:0 lpe; c16_0_lpe). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12905732 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12905732 come from?
GWAS Catalog, Nature communications 2023, PMID:37253714. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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