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Sex hormone-binding globulin levels adjusted for BMI

near RNU2-3P · rs12898856

What the study found

Who was studied 368,929 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0102 higher (95% confidence interval 0.0086-0.0119); p = 5 × 10−36.

How common The C allele had a frequency of about 55% in the people studied.

Where it sits Chromosome 15, band 15q26.2 — between genes, 61.1 kb from RNU2-3P.

What each result means

C/C Two copies of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. That is a smaller link than two copies.
T/T No copy of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. This is the starting point the study compared everyone against.
Source

Questions about rs12898856

What is rs12898856?

rs12898856 is a single position in the genome, in or near the near RNU2-3P gene. Published research associates it with sex hormone-binding globulin levels adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12898856 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12898856 come from?

GWAS Catalog, Nature medicine 2020, PMID:32042192. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sex hormone-binding globulin levels adjusted for BMI (rs12898856). MyGeneLog™. https://www.mygenelog.com/variants/rs12898856

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