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Allergen component sensitization (Hevea brasiliensis 8)

HLA-DRB1 · rs1289784088

What the study found

Who was studied 50 Japanese ancestry pediatric cases, 514 Japanese ancestry pediatric controls.

The effect Each copy of the A allele carried 9.26 times the odds of Allergen component sensitization (Hevea brasiliensis 8) (95% confidence interval 4.648-18.453); p = 5 × 10−10.

How common The A allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — in an intron of HLA-DRB1.

What each result means

A/A Two copies of the version the research linked to Allergen component sensitization (Hevea brasiliensis 8). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Allergen component sensitization (Hevea brasiliensis 8). That is a smaller link than two copies.
T/T No copy of the version the research linked to Allergen component sensitization (Hevea brasiliensis 8). This is the starting point the study compared everyone against.
Source

Questions about rs1289784088

What is rs1289784088?

rs1289784088 is a single position in the genome, in or near the HLA-DRB1 gene. Published research associates it with allergen component sensitization (hevea brasiliensis 8). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1289784088 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1289784088 come from?

GWAS Catalog, The journal of allergy and clinical immunology. Global 2023, PMID:37780799. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Allergen component sensitization (Hevea brasiliensis 8) (rs1289784088). MyGeneLog™. https://www.mygenelog.com/variants/rs1289784088

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