FNDC3B · rs12897
Where this position leads
Condition: Coronary Artery Disease
What the study found
Who was studied up to 122,733 cases, up to 424,528 controls.
The effect Each copy of the A allele shifted the measure 0.0358 lower (95% confidence interval 0.024-0.047); p = 1 × 10−9.
How common The A allele had a frequency of about 59% in the people studied.
Where it sits Chromosome 3, band 3q26.31 — in the 3′ untranslated region of FNDC3B.
rs12897 is a single position in the genome, in or near the FNDC3B gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Circ Res 2017, PMID:29212778. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Coronary artery disease (rs12897). MyGeneLog™. https://www.mygenelog.com/variants/rs12897