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Metabolite levels

SGPP1 · rs12887573

Where this position leads

Condition: Blood Metabolite Levels

rs12887573 Condition: Blood Metabolite Levels Blood Metabolite Levels Condition rs12887573 rs12887573 SGPP1

What the study found

Who was studied 1,954 Chinese ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.205 higher (95% confidence interval 0.14-0.27); p = 3 × 10−9.

How common The T allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 14, band 14q23.2 — in an intron of SYNE2.

What each result means

G/G No copy of the version the research linked to Metabolite levels. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Metabolite levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Metabolite levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12887573

What is rs12887573?

rs12887573 is a single position in the genome, in or near the SGPP1 gene. Published research associates it with metabolite levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12887573 linked to?

On MyGeneLog this position is linked to Blood Metabolite Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs12887573 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12887573 come from?

GWAS Catalog, Human molecular genetics 2020, PMID:31628463. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Metabolite levels (rs12887573). MyGeneLog™. https://www.mygenelog.com/variants/rs12887573

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