Sensitive

Recurrence-free survival in non-muscle-invasive bladder cancer

G2E3 · rs12885353

Where this position leads

Condition: Bladder Cancer

rs12885353 Condition: Bladder Cancer Bladder Cancer Condition rs12885353 rs12885353 G2E3

What the study found

Who was studied 3,400 European ancestry individuals.

The effect Each copy of the C allele carried 1.55 times the odds of Recurrence-free survival in non-muscle-invasive bladder cancer (95% confidence interval 1.33-1.82); p = 4 × 10−8.

Where it sits Chromosome 14, band 14q12 — in an intron of G2E3.

What each result means

C/C Two copies of the version the research linked to Recurrence-free survival in non-muscle-invasive bladder cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Recurrence-free survival in non-muscle-invasive bladder cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Recurrence-free survival in non-muscle-invasive bladder cancer. This is the starting point the study compared everyone against.
Source

Questions about rs12885353

What is rs12885353?

rs12885353 is a single position in the genome, in or near the G2E3 gene. Published research associates it with recurrence-free survival in non-muscle-invasive bladder cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12885353 linked to?

On MyGeneLog this position is linked to Bladder Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs12885353 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12885353 come from?

GWAS Catalog, European urology oncology 2022, PMID:34353775. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Recurrence-free survival in non-muscle-invasive bladder cancer (rs12885353). MyGeneLog™. https://www.mygenelog.com/variants/rs12885353

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