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Glutamine levels

NDRG2 · rs12881221

What the study found

Who was studied 114,751 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0391 lower (95% confidence interval 0.028-0.05); p = 9 × 10−12.

How common The C allele had a frequency of about 84% in the people studied.

Where it sits Chromosome 14, band 14q11.2 — in an intron of NDRG2.

What each result means

C/C Two copies of the version the research linked to Glutamine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Glutamine levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Glutamine levels. This is the starting point the study compared everyone against.
Source

Questions about rs12881221

What is rs12881221?

rs12881221 is a single position in the genome, in or near the NDRG2 gene. Published research associates it with glutamine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12881221 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12881221 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glutamine levels (rs12881221). MyGeneLog™. https://www.mygenelog.com/variants/rs12881221

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