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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 420,576 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0264 lower (95% confidence interval 0.021-0.031); p = 4 × 10−24.
How common The G allele had a frequency of about 36% in the people studied.
Where it sits Chromosome 14, band 14q31.3 — in an intron of PTPN21.
What each result means
A/ANo copy of the version the research linked to creatinine (maximum, inv-norm transformed). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to creatinine (maximum, inv-norm transformed). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to creatinine (maximum, inv-norm transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs1288122
What is rs1288122?
rs1288122 is a single position in the genome, in or near the PTPN21 gene. Published research associates it with creatinine (maximum, inv-norm transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1288122 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1288122 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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