0 1212216Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others6Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 119,274 African American or Afro-Caribbean individuals, 57,979 Hispanic or Latin American individuals, 6,421 East Asian ancestry individuals, 425,680 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0297 lower (95% confidence interval 0.024-0.035); p = 2 × 10−26.
How common The G allele had a frequency of about 60% in the people studied.
Where it sits Chromosome 13, band 13q13.1 — between genes, 125.8 kb from RXFP2.
What each result means
G/GTwo copies of the version the research linked to diastolic blood pressure (DBP, maximum, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to diastolic blood pressure (DBP, maximum, inv-normal transformed). That is a smaller link than two copies.
T/TNo copy of the version the research linked to diastolic blood pressure (DBP, maximum, inv-normal transformed). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs12876275
What is rs12876275?
rs12876275 is a single position in the genome, in or near the near RXFP2 gene. Published research associates it with diastolic blood pressure (dbp, maximum, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12876275 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs12876275 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12876275 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1212216Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others6Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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