0 122316Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others6Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 27,993 European ancestry individuals, 6,949 Black individuals, 6,530 Hispanic individuals, 55 individuals.
The effect
Each copy of the T allele shifted the measure 0 higher (95% confidence interval -0.08428-0.08428); p = 2 × 10−8.
How common The T allele had a frequency of about 91% in the people studied.
Where it sits Chromosome 18, band 18p11.21 — in an intron of LDLRAD4.
What each result means
C/CNo copy of the version the research linked to Alzheimer's disease (age of onset). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Alzheimer's disease (age of onset). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Alzheimer's disease (age of onset). That is the strongest link of the three results. A link in a study is not a diagnosis.
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025 · PMID 40883957 · open access
Questions about rs1284402
What is rs1284402?
rs1284402 is a single position in the genome, in or near the LDLRAD4 gene. Published research associates it with alzheimer's disease (age of onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1284402 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs1284402 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1284402 come from?
GWAS Catalog, Alzheimer's & dementia : the journal of the Alzheimer's Association 2025, PMID:40883957. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 122316Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others6Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Alzheimer's disease (age of onset) (rs1284402). MyGeneLog™. https://www.mygenelog.com/variants/rs1284402