HMGA2 · rs12810758
Where this position leads
Condition: Inguinal Hernia
What the study found
Who was studied 32,089 European, African, Asian, Hispanic/Latin American or mixed ancestry male cases, 196,784 European, African, Asian, Hispanic/Latin American or mixed ancestry male controls.
The effect The reported allele is T; the catalogue records no effect size ; p = 2 × 10−11.
Where it sits Chromosome 12, band 12q14.3 — in an intron of HMGA2.
rs12810758 is a single position in the genome, in or near the HMGA2 gene. Published research associates it with inguinal hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Inguinal Hernia. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Human molecular genetics 2022, PMID:35022708. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Inguinal hernia (rs12810758). MyGeneLog™. https://www.mygenelog.com/variants/rs12810758