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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 650 Amish individuals; replicated in 847 European American ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.351 lower; p = 1 × 10−8.
How common The T allele had a frequency of about 32% in the people studied.
Where it sits Chromosome 11, band 11q12.2 — between genes, 0.8 kb from CD6.
What each result means
C/CNo copy of the version the research linked to Phosphatidylcholines (40:5)A levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Phosphatidylcholines (40:5)A levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Phosphatidylcholines (40:5)A levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2022 · PMID 35393526 · open access
Questions about rs12808046
What is rs12808046?
rs12808046 is a single position in the genome, in or near the near CD6 gene. Published research associates it with phosphatidylcholines (40:5)a levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12808046 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12808046 come from?
GWAS Catalog, Communications biology 2022, PMID:35393526. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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