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Fasting blood glucose

CRY2 · rs12794698

Where this position leads

Condition: Fasting Blood Glucose

rs12794698 Condition: Fasting Blood Glucose Fasting Blood Glucose Condition rs12794698 rs12794698 CRY2

What the study found

Who was studied 153,950 Korean ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0337 lower (95% confidence interval 0.025-0.042); p = 4 × 10−15.

How common The A allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 11, band 11p11.2 — in an intron of CRY2.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Fasting blood glucose compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Fasting blood glucose.
G/G Published research associates this genotype with typical/baseline likelihood of Fasting blood glucose — no copies of the reported risk allele.
Source
Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures
Jee YH, Wang Y, Jung KJ, Lee JY, Kimm H, Duan R, Price AL, Martin AR, Kraft P
Nature communications · 2025 · PMID 40436827 · open access

Questions about rs12794698

What is rs12794698?

rs12794698 is a single position in the genome, in or near the CRY2 gene. Published research associates it with fasting blood glucose. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12794698 linked to?

On MyGeneLog this position is linked to Fasting Blood Glucose. The research behind each link, and its sources, are set out on that condition page.

Does having rs12794698 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12794698 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Fasting blood glucose (rs12794698). MyGeneLog™. https://www.mygenelog.com/variants/rs12794698

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