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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 121,934 European ancestry cases, 591,699 European ancestry controls.
The effect
Each copy of the A allele carried 2.35 times the odds of Age-related hearing impairment; p = 8 × 10−11.
Where it sits Chromosome 10, band 10q23.1 — in an intron of LINC02655.
What each result means
A/ATwo copies of the version the research linked to Age-related hearing impairment. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Age-related hearing impairment. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Age-related hearing impairment. This is the starting point the study compared everyone against.
Communications biology · 2021 · PMID 34108613 · open access
Questions about rs12784122
What is rs12784122?
rs12784122 is a single position in the genome, in or near the SH2D4B gene. Published research associates it with age-related hearing impairment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12784122 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12784122 come from?
GWAS Catalog, Communications biology 2021, PMID:34108613. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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