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Liver IL2RA levels

RBM17 · rs12778662

What the study found

Who was studied 241 European ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 6 × 10−9.

Where it sits Chromosome 10, band 10p15.1 — in an intron of RBM17.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Liver IL2RA levels — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Liver IL2RA levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Liver IL2RA levels compared to the general population.
Source

Questions about rs12778662

What is rs12778662?

rs12778662 is a single position in the genome, in or near the RBM17 gene. Published research associates it with liver il2ra levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12778662 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12778662 come from?

GWAS Catalog, Molecular metabolism 2026, PMID:41456820. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Liver IL2RA levels (rs12778662). MyGeneLog™. https://www.mygenelog.com/variants/rs12778662

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