0 30328123110Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity0Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 120,246 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.024 higher; p = 9 × 10−27.
How common The G allele had a frequency of about 4% in the people studied.
Where it sits Chromosome 5, band 5q31.1 — a synonymous change in MIR3936HG.
What ClinVar records
ClassificationBenign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 3 submitters), last evaluated 2026-01-27.
ClinVar record 805281NM_003059.3(SLC22A4):c.1413C>G (p.Gly471=)
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CNo copy of the version the research linked to Fibrinogen levels. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Fibrinogen levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Fibrinogen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs12777 is a single position in the genome, in or near the SLC22A4 gene. Published research associates it with fibrinogen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12777 linked to?
On MyGeneLog this position is linked to Fibrinogen and Blood Clotting. The research behind each link, and its sources, are set out on that condition page.
Does having rs12777 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12777 come from?
GWAS Catalog, Hum Mol Genet 2015, PMID:26561523. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 30328123110Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity0Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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