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Systolic blood pressure (UKB data field 4080)

FGGY-DT · rs12755444

Where this position leads

Condition: Blood Pressure

rs12755444 Condition: Blood Pressure Blood Pressure Condition rs12755444 rs12755444 FGGY-DT

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0169 lower (95% confidence interval 0.013-0.021); p = 2 × 10−16.

How common The G allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 1, band 1p32.1 — in an intron of FGGY-DT.

What each result means

A/A No copy of the version the research linked to Systolic blood pressure (UKB data field 4080). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Systolic blood pressure (UKB data field 4080). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Systolic blood pressure (UKB data field 4080). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12755444

What is rs12755444?

rs12755444 is a single position in the genome, in or near the FGGY-DT gene. Published research associates it with systolic blood pressure (ukb data field 4080). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12755444 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs12755444 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12755444 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Systolic blood pressure (UKB data field 4080) (rs12755444). MyGeneLog™. https://www.mygenelog.com/variants/rs12755444

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