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Rate of cognitive decline in mild cognitive impairment (time interaction)

ACOT11 · rs12752888

What the study found

Who was studied 822 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 3 × 10−11.

Where it sits Chromosome 1, band 1p32.3 — in an intron of LINC02784.

What each result means

C/C Two copies of the version the research linked to Rate of cognitive decline in mild cognitive impairment (time interaction). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Rate of cognitive decline in mild cognitive impairment (time interaction). That is a smaller link than two copies.
T/T No copy of the version the research linked to Rate of cognitive decline in mild cognitive impairment (time interaction). This is the starting point the study compared everyone against.
Source

Questions about rs12752888

What is rs12752888?

rs12752888 is a single position in the genome, in or near the ACOT11 gene. Published research associates it with rate of cognitive decline in mild cognitive impairment (time interaction). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12752888 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12752888 come from?

GWAS Catalog, Transl Psychiatry 2011, PMID:22833209. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Rate of cognitive decline in mild cognitive impairment (time interaction) (rs12752888). MyGeneLog™. https://www.mygenelog.com/variants/rs12752888

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