C/CPublished research associates this genotype with typical/baseline likelihood of C-reactive protein levels or HDL-cholesterol levels (pleiotropy) — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with C-reactive protein levels or HDL-cholesterol levels (pleiotropy).
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of C-reactive protein levels or HDL-cholesterol levels (pleiotropy) compared to the general population.
rs12742376 is a single position in the genome, in or near the C1orf172 gene. Published research associates it with c-reactive protein levels or hdl-cholesterol levels (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12742376 linked to?
On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs12742376 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12742376 come from?
GWAS Catalog, BMC Genomics 2016, PMID:27286809. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.