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Obesity (PheCode 278.1)

near EEF1A1P11 · rs12739556

Where this position leads

Condition: Obesity and Body Weight

rs12739556 Condition: Obesity and Body Weight Obesity and Body Weight Condition rs12739556 rs12739556 near EEF1A1P…

What the study found

Who was studied 169,600 European ancestry cases, 244,254 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.0378 lower (95% confidence interval 0.028-0.048); p = 1 × 10−17.

How common The C allele had a frequency of about 72% in the people studied.

Where it sits Chromosome 1, band 1p21.3 — between genes, 64 kb from EEF1A1P11.

What each result means

C/C Two copies of the version the research linked to Obesity (PheCode 278.1). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Obesity (PheCode 278.1). That is a smaller link than two copies.
T/T No copy of the version the research linked to Obesity (PheCode 278.1). This is the starting point the study compared everyone against.
Source

Questions about rs12739556

What is rs12739556?

rs12739556 is a single position in the genome, in or near the near EEF1A1P11 gene. Published research associates it with obesity (phecode 278.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12739556 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs12739556 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12739556 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Obesity (PheCode 278.1) (rs12739556). MyGeneLog™. https://www.mygenelog.com/variants/rs12739556

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