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Urate levels

ARID1A · rs12738345

What the study found

Who was studied 454,183 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0319 lower (95% confidence interval 0.025-0.039); p = 3 × 10−21.

How common The T allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 1, band 1p36.11 — in the 5′ untranslated region of ARID1A.

What each result means

C/C No copy of the version the research linked to Urate levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Urate levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Urate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12738345

What is rs12738345?

rs12738345 is a single position in the genome, in or near the ARID1A gene. Published research associates it with urate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12738345 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12738345 come from?

GWAS Catalog, Hypertension (Dallas, Tex. : 1979) 2021, PMID:33356394. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Urate levels (rs12738345). MyGeneLog™. https://www.mygenelog.com/variants/rs12738345

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