0 172213Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others13Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 16,201 African American or Afro-Caribbean individuals.
The effect
Each copy of the T allele shifted the measure 0.307 higher (95% confidence interval 0.27-0.34); p = 6 × 10−75.
How common The T allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 1, band 1q21.3 — between genes, 2.9 kb from SPRR5.
What each result means
C/CNo copy of the version the research linked to White blood cell count. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to White blood cell count. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to White blood cell count. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs12734348 is a single position in the genome, in or near the near SPRR5 gene. Published research associates it with white blood cell count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12734348 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs12734348 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12734348 come from?
GWAS Catalog, BMC genomics 2021, PMID:34107879. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 172213Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others13Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
White blood cell count (rs12734348). MyGeneLog™. https://www.mygenelog.com/variants/rs12734348