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MFAP4 protein levels

DIPK1A · rs12733767

Where this position leads

Condition: Celiac Disease

rs12733767 Condition: Celiac Disease Celiac Disease Condition rs12733767 rs12733767 DIPK1A

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0791 higher (95% confidence interval 0.06-0.098); p = 4 × 10−18.

How common The T allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 1, band 1p22.1 — in an intron of DIPK1A.

What each result means

C/C No copy of the version the research linked to MFAP4 protein levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to MFAP4 protein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to MFAP4 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12733767

What is rs12733767?

rs12733767 is a single position in the genome, in or near the DIPK1A gene. Published research associates it with mfap4 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12733767 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs12733767 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12733767 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

MFAP4 protein levels (rs12733767). MyGeneLog™. https://www.mygenelog.com/variants/rs12733767

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