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VCAM1 protein levels

near VCAM1 · rs12732056

Where this position leads

Condition: Celiac Disease

rs12732056 Condition: Celiac Disease Celiac Disease Condition rs12732056 rs12732056 near VCAM1

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0725 higher (95% confidence interval 0.057-0.088); p = 2 × 10−24.

How common The T allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 1, band 1p21.2 — between genes, 2.1 kb from VCAM1.

What each result means

A/A No copy of the version the research linked to VCAM1 protein levels. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to VCAM1 protein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to VCAM1 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12732056

What is rs12732056?

rs12732056 is a single position in the genome, in or near the near VCAM1 gene. Published research associates it with vcam1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12732056 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs12732056 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12732056 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

VCAM1 protein levels (rs12732056). MyGeneLog™. https://www.mygenelog.com/variants/rs12732056

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