Standard

Urinary albumin excretion

FMO4 · rs12727104

Where this position leads

Condition: Kidney Function

rs12727104 Condition: Kidney Function Kidney Function Condition rs12727104 rs12727104 FMO4

What the study found

Who was studied 382,500 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0161 higher (95% confidence interval 0.011-0.022); p = 1 × 10−8.

How common The G allele had a frequency of about 90% in the people studied.

Where it sits Chromosome 1, band 1q24.3 — between genes, 9.1 kb from CYCSP53.

What each result means

A/A No copy of the version the research linked to Urinary albumin excretion. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Urinary albumin excretion. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Urinary albumin excretion. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12727104

What is rs12727104?

rs12727104 is a single position in the genome, in or near the FMO4 gene. Published research associates it with urinary albumin excretion. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12727104 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs12727104 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12727104 come from?

GWAS Catalog, American journal of human genetics 2018, PMID:30220432. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urinary albumin excretion (rs12727104). MyGeneLog™. https://www.mygenelog.com/variants/rs12727104

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