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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 3,677 Finnish ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.298 SD units higher; p = 9 × 10−20.
Where it sits Chromosome 10, band 10p15.1 — in an intron of IL2RA.
What each result means
C/CTwo copies of the version the research linked to Interleukin-2 receptor antagonist levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Interleukin-2 receptor antagonist levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Interleukin-2 receptor antagonist levels. This is the starting point the study compared everyone against.
American journal of human genetics · 2017 · PMID 27989323
Questions about rs12722588
What is rs12722588?
rs12722588 is a single position in the genome, in or near the IL2RA gene. Published research associates it with interleukin-2 receptor antagonist levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12722588 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12722588 come from?
GWAS Catalog, American journal of human genetics 2017, PMID:27989323. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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