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LDL cholesterol

APOB · rs12713956

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs12713956 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs12713956 rs12713956 APOB

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of LDL cholesterol — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with LDL cholesterol.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of LDL cholesterol compared to the general population.
Source
Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations
Coram MA, Duan Q, Hoffmann TJ, Thornton T, Knowles JW, Johnson NA, Ochs-Balcom HM, Donlon TA, Martin LW, Eaton CB, Robinson JG, Risch NJ
and 5 more — show all
Zhu X, Kooperberg C, Li Y, Reiner AP, Tang H
American journal of human genetics · 2013 · PMID 23726366

Questions about rs12713956

What is rs12713956?

rs12713956 is a single position in the genome, in or near the APOB gene. Published research associates it with ldl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12713956 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs12713956 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12713956 come from?

GWAS Catalog, Am J Hum Genet 2013, PMID:23726366. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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