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Who was studied 7,861 African American individuals, 3,425 Hispanic individuals; replicated in 7,138 African American individuals.
The effect
Each copy of the G allele shifted the measure 4.86 lower; p = 4 × 10−8.
How common The G allele had a frequency of about 18% in the people studied.
Where it sits Chromosome 2, band 2p24.1 — in an intron of APOB.
What each result means
A/ANo copy of the version the research linked to LDL cholesterol. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to LDL cholesterol. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to LDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of human genetics · 2013 · PMID 23726366
Questions about rs12713956
What is rs12713956?
rs12713956 is a single position in the genome, in or near the APOB gene. Published research associates it with ldl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12713956 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs12713956 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12713956 come from?
GWAS Catalog, Am J Hum Genet 2013, PMID:23726366. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 31321822310Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others10Total31Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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