0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 17,054 European, Japanese ancestry endometriosis cases, 19,554 European, Japanese ancestry asthma cases, 483,220 European, Japanese ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.062 higher; p = 2 × 10−11.
Where it sits Chromosome 15, band 15q22.33 — in an intron of SMAD3.
What each result means
C/CNo copy of the version the research linked to Endometriosis or asthma (pleiotropy). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Endometriosis or asthma (pleiotropy). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Endometriosis or asthma (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
Human reproduction (Oxford, England) · 2022 · PMID 35472084
Questions about rs12708492
What is rs12708492?
rs12708492 is a single position in the genome, in or near the SMAD3 gene. Published research associates it with endometriosis or asthma (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12708492 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs12708492 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12708492 come from?
GWAS Catalog, Human reproduction (Oxford, England) 2022, PMID:35472084. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Endometriosis or asthma (pleiotropy) (rs12708492). MyGeneLog™. https://www.mygenelog.com/variants/rs12708492