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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 325,027 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0154 higher (95% confidence interval 0.011-0.02); p = 2 × 10−10.
Where it sits Chromosome 7, band 7q21.11 — between genes, 110.4 kb from HMGN2P11.
What each result means
C/CTwo copies of the version the research linked to Chronic obstructive pulmonary disease liability (machine learning-based score). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Chronic obstructive pulmonary disease liability (machine learning-based score). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Chronic obstructive pulmonary disease liability (machine learning-based score). This is the starting point the study compared everyone against.
rs12707676 is a single position in the genome, in or near the near HMGN2P11 gene. Published research associates it with chronic obstructive pulmonary disease liability (machine learning-based score). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12707676 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12707676 come from?
GWAS Catalog, Nature genetics 2023, PMID:37069358. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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