CALD1 · rs12707188
Where this position leads
Condition: Umbilical Hernia
What the study found
Who was studied 5,356 European ancestry cases, 26,780 European ancestry controls.
The effect Each copy of the T allele carried 1.19 times the odds of Umbilical hernia (95% confidence interval 1.14-1.24); p = 5 × 10−15.
How common The T allele had a frequency of about 37% in the people studied.
Where it sits Chromosome 7, band 7q33 — in an intron of CALD1.
rs12707188 is a single position in the genome, in or near the CALD1 gene. Published research associates it with umbilical hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Umbilical Hernia. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PloS one 2022, PMID:36584111. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Umbilical hernia (rs12707188). MyGeneLog™. https://www.mygenelog.com/variants/rs12707188