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Sex hormone-binding globulin levels adjusted for BMI

SRRT · rs12705095

What the study found

Who was studied 180,094 European ancestry men.

The effect Each copy of the G allele shifted the measure 0.0175 higher (95% confidence interval 0.015-0.02); p = 3 × 10−35.

How common The G allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 7, band 7q22.1 — in an intron of SRRT.

What each result means

G/G Two copies of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. That is a smaller link than two copies.
T/T No copy of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. This is the starting point the study compared everyone against.
Source

Questions about rs12705095

What is rs12705095?

rs12705095 is a single position in the genome, in or near the SRRT gene. Published research associates it with sex hormone-binding globulin levels adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12705095 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12705095 come from?

GWAS Catalog, Nature medicine 2020, PMID:32042192. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sex hormone-binding globulin levels adjusted for BMI (rs12705095). MyGeneLog™. https://www.mygenelog.com/variants/rs12705095

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