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Telomere length

TERC · rs12696304

Where this position leads

Condition: Telomere Length and Epigenetic Age Acceleration

rs12696304 Condition: Telomere Length and Epigenetic Age Acceleration Telomere Length and Epigenetic Age … Condition Topic: Blood sugar and insulin Blood sugar and insulin Topic rs12696304 rs12696304 TERC

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied 2,917 European ancestry individuals; replicated in 9,492 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.11 lower (95% confidence interval 0.08-0.14); p = 4 × 10−14.

How common The G allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 3, band 3q26.2 — between genes, 1.1 kb from TERC.

What each result means

C/C No copy of the version the research linked to Telomere length. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Telomere length. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Telomere length. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs12696304

What is rs12696304?

rs12696304 is a single position in the genome, in or near the TERC gene. Published research associates it with telomere length. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12696304 linked to?

On MyGeneLog this position is linked to Telomere Length and Epigenetic Age Acceleration. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs12696304?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (3 papers), brain and memory (2 papers), alcohol and the flush (1 papers), heart and circulation (1 papers), kidneys (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs12696304 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12696304 come from?

GWAS Catalog, Nat Genet 2010, PMID:20139977. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Telomere length (rs12696304). MyGeneLog™. https://www.mygenelog.com/variants/rs12696304

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