Standard

Triglyceride percentage of total lipids in intermediate-density lipoprotein

near COBLL1 · rs12692735

What the study found

Who was studied 199,732 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0287 lower (95% confidence interval 0.022-0.035); p = 2 × 10−19.

How common The T allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 2, band 2q24.3 — between genes, 5.6 kb from COBLL1.

What each result means

G/G No copy of the version the research linked to Triglyceride percentage of total lipids in intermediate-density lipoprotein. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Triglyceride percentage of total lipids in intermediate-density lipoprotein. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Triglyceride percentage of total lipids in intermediate-density lipoprotein. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12692735

What is rs12692735?

rs12692735 is a single position in the genome, in or near the near COBLL1 gene. Published research associates it with triglyceride percentage of total lipids in intermediate-density lipoprotein. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12692735 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12692735 come from?

GWAS Catalog, British journal of cancer 2025, PMID:40307439. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglyceride percentage of total lipids in intermediate-density lipoprotein (rs12692735). MyGeneLog™. https://www.mygenelog.com/variants/rs12692735

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