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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,832 European ancestry individuals; replicated in 1,104 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.188 pmol/L lower; p = 2 × 10−11.
How common The T allele had a frequency of about 13% in the people studied.
Where it sits Chromosome X, band Xq22.3 — between genes, 6.7 kb from CTDSPL2P2.
What each result means
C/CNo copy of the version the research linked to Free triiodothyronine (T3) levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Free triiodothyronine (T3) levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Free triiodothyronine (T3) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
European journal of endocrinology · 2021 · PMID 34524976
Questions about rs12687280
What is rs12687280?
rs12687280 is a single position in the genome, in or near the near CTDSPL2P2 gene. Published research associates it with free triiodothyronine (t3) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12687280 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12687280 come from?
GWAS Catalog, European journal of endocrinology 2021, PMID:34524976. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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