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Who was studied 18,122 Han Chinese ancestry individuals; replicated in 1,989 Han Chinese ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.089 higher (95% confidence interval 0.065-0.113); p = 2 × 10−13.
How common The A allele had a frequency of about 26% in the people studied.
Where it sits Chromosome 9, band 9p24.3 — in an intron of KANK1.
What each result means
A/ATwo copies of the version the research linked to Fasting blood glucose. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Fasting blood glucose. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Fasting blood glucose. This is the starting point the study compared everyone against.
rs12684488 is a single position in the genome, in or near the KANK1 gene. Published research associates it with fasting blood glucose. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12684488 linked to?
On MyGeneLog this position is linked to Fasting Blood Glucose. The research behind each link, and its sources, are set out on that condition page.
Does having rs12684488 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12684488 come from?
GWAS Catalog, Diabetologia 2021, PMID:33842983. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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